Anticorps Recombinant de lapin anti-NKp46/NCR1

NKp46/NCR1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 750 Fluorescent Dye

CloneNo.

241804A12

N° de cat : CL750-98198

Synonymes

Ncr1, 241804A12, Activating receptor 1, CD335, Ly94

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Galerie de données de validation

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  FC experiment of mouse splenocytes using CL750-98198

  1x10^6 mouse splenocytes were surface stained with CoraLite® Plus 488 Anti-Mouse CD49b, and 0.25 ug CoraLite® Plus 750 Anti-Mouse NKp46/NCR1 Rabbit RecAb (CL750-98198, Clone: 241804A12) or CoraLite® Plus 750 Rabbit IgG Isotype Control RecAb (CL750-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using CL750-98198

  1x10^6 mouse splenocytes were surface stained with 0.25 ug CoraLite® Plus 750 Anti-Mouse NKp46/NCR1 Rabbit RecAb (CL750-98198, Clone: 241804A12) (red) or CoraLite® Plus 750 Rabbit IgG Isotype Control RecAb (CL750-98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL750-98198 cible NKp46/NCR1 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: NKp46/NCR1 Protéine recombinante Eg1825
• Nom complet: natural cytotoxicity triggering receptor 1
• Masse moléculaire calculée: 37kDa
• Numéro d’acquisition GenBank: NM_010746.3
• Symbole du gène: NKp46/NCR1
• Identification du gène (NCBI): 17086
• Conjugaison: CoraLite® Plus 750 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 755 nm / 780 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

NKp46, also known as NCR1 or CD335, is an Ig-like superfamily cell surface receptor that is highly conserved in mammals (PMID: 22021440). NKp46 is a type I transmembrane glycoprotein consisting of two extracellular Ig-like domains, a transmembrane domain, and an intracellular tail (PMID: 9730896). It is expressed on NK cells, rare T-cell subsets and a mucosal population of NKp46+ innate lymphoid cells (PMID: 9730896; 22021440). NKp46 is the major triggering receptor involved in the natural cytotoxicity (PMID: 10359120; 10092106; 15356098).

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