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Anticorps Recombinant de lapin anti-NLRP7

NLRP7 Recombinant Antibody for IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241120A10

N° de cat : 83996-4-PBS

Synonymes

NOD12, NALP7, NACHT, LRR and PYD domains-containing protein 7, HYDM, CLR19.4

Galerie de données de validation

Filter:
  • Immunofluorescence (IF) / fluorescent staining of K-562 cells using NLRP7 Recombinant antibody (83996-4-RR)

    IF Staining of K-562 using 83996-4-RR (same clone as 83996-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed K-562 cells using NLRP7 antibody (83996-4-RR, Clone: 241120A10 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83996-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83996-4-RR

    Affinity and Kinetic Characterization of 83996-4-RR

    Biolayer interferometry (BLl) kinetic assays of 83996-4-RR against Human NLRP7 were performed. The affinity constant is 1.98 nM.

Informations sur le produit

83996-4-PBS cible NLRP7 dans les applications de IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène NLRP7 Protéine recombinante Ag27465
Nom complet NLR family, pyrin domain containing 7
Masse moléculaire calculée112 kDa, 115 kDa, 118 kDa
Numéro d’acquisition GenBankBC109125
Symbole du gène NLRP7
Identification du gène (NCBI) 199713
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NLRP7, also called NALP7 or PYPAF3, is a member of the NOD-like receptors (NLR), a family of proteins that plays a crucial role in the innate immune response. NLRP7 has been reported to emerge from NLRP2 gene. Similar to all inflammasomes, NLRP7 contributes to both pro- and an anti-inflammatory processes, depending on whether it functions in an inflammasome-dependent or independent pathway. The function of NLRP7 inflammasome has also been reported to depend on the master regulatory transcription factor protein that controls cellular inflammation, the NF-kB. In addition to its pro- and anti-inflammatory actions, NLRP7 plays a role in restricting intracellular bacterial replication and can also induce inflammasome assembly upon specific stimulation by FSL-1 (diacylated lipoprotein).

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