Anticorps Polyclonal de lapin anti-NOL7

• Phare
• Validé par KD/KO

NOL7 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

Conjugaison

Non conjugué

N° de cat : 18424-1-PBS

Synonymes

C6orf90, NOP27, Nucleolar protein 7, nucleolar protein 7, 27kDa, Nucleolar protein of 27 kDa

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Galerie de données de validation

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  WB analysis using 18424-1-AP (same clone as 18424-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 18424-1-AP (NOL7 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 18424-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 18424-1-AP (same clone as 18424-1-PBS)

  WB result of NOL7 antibody (18424-1-AP; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-NOL7 transfected HEK-293 cells. This data was developed using the same antibody clone with 18424-1-PBS in a different storage buffer formulation.

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Informations sur le produit

18424-1-PBS cible NOL7 dans les applications de et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NOL7 Protéine recombinante Ag13272
• Nom complet: nucleolar protein 7, 27kDa
• Masse moléculaire calculée: 257 aa, 29 kDa
• Poids moléculaire observé: 38 kDa
• Numéro d’acquisition GenBank: BC023517
• Symbole du gène: NOL7
• Identification du gène (NCBI): 51406
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NOL7 (nucleolar protein 7) is localized in both the nucleolus and nucleoplasm, with its nucleolar localization being RNA-dependent. Its function in the nucleolus is likely related to maintaining nucleolar structure and cell growth, while its role in the nucleoplasm may be associated with anti-angiogenic effects. Additionally, NOL7 is involved in the accumulation of early pre-rRNA and the processing of pre-18S rRNA, which are crucial for maintaining nucleolar function and cell growth. The expression of NOL7 is regulated by various transcription factors, including c-myc and RXRα. In cervical cancer, NOL7 transcription is also positively regulated by the RB tumor suppressor gene. The NOL7 gene encodes three distinct splice variants, each with different intracellular localizations that may affect their functions.

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