Anticorps Monoclonal anti-NONO

NONO Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

2A2B10

N° de cat : 66361-1-PBS

Synonymes

2A2B10, 54 kDa nuclear RNA- and DNA-binding protein, 55 kDa nuclear protein, NonO protein, Non-POU domain-containing octamer-binding protein

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Galerie de données de validation

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  WB analysis of C2C12 using 66361-1-Ig (same clone as 66361-1-PBS)

  C2C12 cell were subjected to SDS PAGE followed by western blot with 66361-1-Ig (NONO Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66361-1-PBS in a different storage buffer formulation.

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  WB analysis of ROS1728 using 66361-1-Ig (same clone as 66361-1-PBS)

  ROS1728 cells were subjected to SDS PAGE followed by western blot with 66361-1-Ig (NONO Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66361-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse skeletal muscle using 66361-1-Ig (same clone as 66361-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 66361-1-Ig (NONO Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66361-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66361-1-PBS cible NONO dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: NONO Protéine recombinante Ag17609
• Nom complet: non-POU domain containing, octamer-binding
• Masse moléculaire calculée: 54 kDa
• Poids moléculaire observé: 54 kDa
• Numéro d’acquisition GenBank: BC010049
• Symbole du gène: NONO
• Identification du gène (NCBI): 4841
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Non-pou domain-containing octamer-binding protein(NONO), other named p54nrb, belongs to DBHS family, whose protein are predominately nuclear and involves in transcriptional and posttranscriptional gene regulatory functions as well as DNA repair. This family has roles in a wide range of biological processes, such as the regulation of circadian rhythm, carcinogenesis and progression of cancer. NONO forms heterodimer with SFPQ, and has been implicated in nuclear retention of A- to I-edited RNA as paraspeckle components, pre-mRAN 3'-end formation, cAMP cycling and transcriptional activation.

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