Anticorps Polyclonal de lapin anti-NOTCH4

NOTCH4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 33280-1-PBS

Synonymes

hNotch4, INT3, Notch 4, Notch 4 extracellular truncation, Notch 4 intracellular domain

---

Galerie de données de validation

• 

  WB analysis using 33280-1-AP (same clone as 33280-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 33280-1-AP (NOTCH4 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 33280-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

33280-1-PBS cible NOTCH4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NOTCH4 Protéine recombinante Ag36738
• Nom complet: Notch homolog 4 (Drosophila)
• Masse moléculaire calculée: 2003 aa, 210 kDa
• Poids moléculaire observé: 210 kDa
• Numéro d’acquisition GenBank: BC140782
• Symbole du gène: NOTCH4
• Identification du gène (NCBI): 4855
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Neurogenic locus notch homolog protein 4 (NOTCH4) is a receptor involved in the Notch signaling pathway, which is synthesized as a precursor that undergoes proteolytic cleavage to form an active receptor. NOTCH4 interacts with various ligands, leading to the release of the Notch intracellular domain (NICD), which translocates to the nucleus and regulates gene expression (PMID: 28794168; 19379690; 17148788). NOTCH4 is involved in various biological processes, including embryonic development, immune cell differentiation, and tumorigenesis (PMID: 24667410; 34925319).

{{ptg:RelatedPrimaryAntibodies}}