Anticorps Recombinant de lapin anti-NOX1
NOX1 Recombinant Antibody for WB, Indirect ELISA
Hôte / Isotype
Lapin / IgG
Réactivité testée
Humain, souris
Applications
WB, Indirect ELISA
Conjugaison
Non conjugué
CloneNo.
241935E7
N° de cat : 84700-1-PBS
Synonymes
Galerie de données de validation
Informations sur le produit
84700-1-PBS cible NOX1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris
Réactivité | Humain, souris |
Hôte / Isotype | Lapin / IgG |
Clonalité | Recombinant |
Type | Anticorps |
Immunogène | NOX1 Protéine recombinante Ag12187 |
Nom complet | NADPH oxidase 1 |
Masse moléculaire calculée | 564 aa, 65 kDa |
Poids moléculaire observé | 59 kDa |
Numéro d’acquisition GenBank | BC075014 |
Symbole du gène | NOX1 |
Identification du gène (NCBI) | 27035 |
Conjugaison | Non conjugué |
Forme | Liquide |
Méthode de purification | Protein A purfication |
Tampon de stockage | PBS only |
Conditions de stockage | Store at -80°C. 20ul contiennent 0,1% de BSA. |
Informations générales
NNOX1(NADPH oxidase 1) is also named as MOX1, NOH1 and belongs to the reactive oxygen species (ROS)-generating NADPH oxidase family. It plays a role in host defense, cell growth and differentiation, cell migration, and malignant transformation(PMID:20351171). It also can mediate oncogenic Ras-induced upregulation of VEGF and angiogenesis by activating Sp1 through Ras-ERK-dependent phosphorylation of Sp1(PMID:18454179). It has 3 isoforms produced by alternative splicing with the molecular weight of 65 kDa, 22 kDa and 59 kDa. The full length protein has two glycosylation sites. It always can be detected two bands of 63 kDa and 55 kDa in cells by western blot or another lower band of 45 kDa which is not likely due to alternative translation or splice variation, but as adjustment for the signal peptide and tag removal(PMID:17560373) or unspecifc(PMID:17460729).