Anticorps Recombinant de lapin anti-NPM3

NPM3 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242863C5

N° de cat : 85156-4-PBS

Synonymes

TMEM123, PORMIN, Nucleoplasmin-3, Nucleoplasmin 3, nucleophosmin/nucleoplasmin, 3

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Galerie de données de validation

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  WB analysis using 85156-4-RR (same clone as 85156-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85156-4-RR (NPM3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85156-4-PBS in a different storage buffer formulation.

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Informations sur le produit

85156-4-PBS cible NPM3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: NPM3 Protéine recombinante Ag2564
• Nom complet: nucleophosmin/nucleoplasmin, 3
• Masse moléculaire calculée: 178 aa, 19 kDa
• Poids moléculaire observé: 20-25 kDa
• Numéro d’acquisition GenBank: BC054868
• Symbole du gène: NPM3
• Identification du gène (NCBI): 10360
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NPM3, a member of the nucleophosmin/ nucleoplasmin family, lacks intrinsic histone chaperone activity, inhibits histone assembly activity of NPM1 in vitro, and dramatically enhances transcription in a cellular system(PMID: 20073534). Human NPM3 is an abundant and widely expressed protein with primarily nuclear localization. The NPM3 protein migrated in SDS-PAGE gels as a doublet with apparent molecular masses of 25 and 27 kDa, which are larger than the 20.5 kDa mass predicted by the deduced amino acid sequence including the HA tag (PMID: 11722795). The NPM3 antibody can detect two bands with MW between 20-27 kDa.

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