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Anticorps Polyclonal de lapin anti-NPR2

NPR2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 55113-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of transfected cells using NPR2 Polyclonal antibody (55113-1-AP)

    WB analysis of transfected cells using 55113-1-AP (same clone as 55113-1-PBS)

    WB result of anti-NPR2 (55113-1-AP, 1:1000) with HEK293 overexpressed NPR2 by Jeremy Egbert and Laurinda Jaffe. (Another anti serum 6328 as control). This data was developed using the same antibody clone with 55113-1-PBS in a different storage buffer formulation.

Informations sur le produit

55113-1-PBS cible NPR2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène Peptide
Nom complet natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
Masse moléculaire calculée 117 kDa
Poids moléculaire observé 111 kDa, 117 kDa
Numéro d’acquisition GenBankNM_003995
Symbole du gène NPR2
Identification du gène (NCBI) 4882
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NPR2, also named as ANPRB, GC-B, NPR-B, ANPR-B and ANP-B, belongs to the adenylyl cyclase class-4/guanylyl cyclase family. It is a receptor for the C-type natriuretic peptide NPPC/CNP hormone. NRP2 has guanylate cyclase activity upon binding of its ligand. It may play a role in the regulation of skeletal growth. NPR2 is the primary receptor for C type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Defects in NPR2 are the cause of acromesomelic dysplasia Maroteaux type (AMDM). The antibody is specific to NPR2.

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