Anticorps Monoclonal anti-NR1H2

• Phare
• Validé par KD/KO

NR1H2 Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

1E12B10

N° de cat : 60345-1-PBS

Synonymes

1E12B10, Liver X receptor beta, LXR b, LXRB, NER

---

Galerie de données de validation

• 

  WB analysis of human liver using 60345-1-Ig (same clone as 60345-1-PBS)

  human liver tissue were subjected to SDS PAGE followed by western blot with 60345-1-Ig (NR1H2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60345-1-PBS in a different storage buffer formulation.

• 

  WB analysis of pig liver using 60345-1-Ig (same clone as 60345-1-PBS)

  pig liver tissue were subjected to SDS PAGE followed by western blot with 60345-1-Ig (NR1H2 Antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60345-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

60345-1-PBS cible NR1H2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain, porc

• Réactivité: Humain, porc
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: NR1H2 Protéine recombinante Ag5635
• Nom complet: nuclear receptor subfamily 1, group H, member 2
• Masse moléculaire calculée: 51 kDa
• Poids moléculaire observé: 51 kDa
• Numéro d’acquisition GenBank: BC047750
• Symbole du gène: NR1H2
• Identification du gène (NCBI): 7376
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NR1H2, also known as LXRB, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It preferentially bind to double-stranded oligonucleotide direct repeats, which have the consensus half-site sequence 5'-AGGTCA-3' and 4-nt spacing (DR-4). It involves in the regulation of cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8.

{{ptg:RelatedPrimaryAntibodies}}