Anticorps Monoclonal anti-NR1H3

NR1H3 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

4A4F7

N° de cat : 60134-1-PBS

Synonymes

Oxysterols receptor LXR alpha, LXRα, LXRA, LXR a, Liver X receptor alpha

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Galerie de données de validation

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  WB analysis using 60134-1-Ig (same clone as 60134-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60134-1-Ig (NR1H3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

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  WB analysis of MCF-7 using 60134-1-Ig (same clone as 60134-1-PBS)

  MCF7 cells were subjected to SDS PAGE followed by western blot with 60134-1-Ig (NR1H3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 60134-1-Ig (same clone as 60134-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 60134-1-Ig (NR1H3 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

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Informations sur le produit

60134-1-PBS cible NR1H3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat

• Réactivité: Humain, porc, rat
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: NR1H3 Protéine recombinante Ag6184
• Nom complet: nuclear receptor subfamily 1, group H, member 3
• Masse moléculaire calculée: 50 kDa
• Poids moléculaire observé: 44 kDa
• Numéro d’acquisition GenBank: BC041172
• Symbole du gène: NR1H3
• Identification du gène (NCBI): 10062
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.

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