Anticorps Polyclonal de lapin anti-NR2E3

• Phare
• Validé par KD/KO

NR2E3 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, porc, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 14246-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 14246-1-AP (same clone as 14246-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 14246-1-AP (NR2E3 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 14246-1-AP (same clone as 14246-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 14246-1-AP (NR2E3 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

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  WB analysis of HepG2 using 14246-1-AP (same clone as 14246-1-PBS)

  HepG2 cells were subjected to SDS PAGE followed by western blot with 14246-1-AP (NR2E3 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

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  WB analysis of Y79 using 14246-1-AP (same clone as 14246-1-PBS)

  Y79 cells were subjected to SDS PAGE followed by western blot with 14246-1-AP (NR2E3 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer using 14246-1-AP (NR2E3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer using 14246-1-AP (NR2E3 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

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  IF Staining of photoreceptor progenitor cells using 14246-1-AP (same clone as 14246-1-PBS)

  IF result of NR2E3 antibody (14246-1-AP, 1:50) with human photoreceptor progenitors cells. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

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Informations sur le produit

14246-1-PBS cible NR2E3 dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NR2E3 Protéine recombinante Ag5503
• Nom complet: nuclear receptor subfamily 2, group E, member 3
• Masse moléculaire calculée: 45 kDa
• Poids moléculaire observé: 43-45 kDa
• Numéro d’acquisition GenBank: BC041421
• Symbole du gène: NR2E3
• Identification du gène (NCBI): 10002
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]

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