Anticorps Polyclonal de lapin anti-NRAMP1

NRAMP1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32308-1-PBS

Synonymes

SLC11A1, NRAMP 1

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Galerie de données de validation

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  WB analysis using 32308-1-AP (same clone as 32308-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32308-1-AP (NRAMP1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32308-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 32308-1-AP (same clone as 32308-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32308-1-AP (NRAMP1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32308-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32308-1-PBS cible NRAMP1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
• Masse moléculaire calculée: 432 aa, 48 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC071165
• Symbole du gène: SLC11A1
• Identification du gène (NCBI): 6556
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

SLC11A1 also known as NRAMP1, belongs to the SLC11 family of solute carriers, which mediate the transport of divalent metals. NRAMP1 is a divalent metal importer specifically expressed in the membranes of late endosomes/lysosomes of professional phagocytes. It plays a crucial role in the defense against intracellular pathogens by depleting essential metal ions from endocytosed microbes, thereby preventing their proliferation(PMID: 24832660, PMID: 39824808).

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