Anticorps Polyclonal de lapin anti-NRD1

NRD1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 15630-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 15630-1-AP (same clone as 15630-1-PBS)

  K-562 cells lysates were subjected to SDS PAGE followed by western blot with 15630-1-AP (NRD1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 15630-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse testis using 15630-1-AP (same clone as 15630-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse testis tissue slide using 15630-1-AP (NRD1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 15630-1-PBS in a different storage buffer formulation.

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  IHC staining of human testis using 15630-1-AP (same clone as 15630-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 15630-1-AP (NRD1 antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 15630-1-PBS in a different storage buffer formulation.

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Informations sur le produit

15630-1-PBS cible NRD1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NRD1 Protéine recombinante Ag7923
• Nom complet: nardilysin (N-arginine dibasic convertase)
• Masse moléculaire calculée: 132 kDa
• Poids moléculaire observé: 135-140 kDa
• Numéro d’acquisition GenBank: BC008775
• Symbole du gène: NRD1
• Identification du gène (NCBI): 4898
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NRD1(Nardilysin) is also named as NRD-C(N-arginine dibasic convertase). It is a zinc metalloendopeptidase of the M16 pitrilysin family that cleaves peptides at dibasic residues. The enzyme has also been found in neural tissues of mouse embryos indicating a role in neural development. Although nardilysin is primarily found in the cytosol, it has been reported that nardilysin is located on the cell surface acting as a receptor for heparinbinding EGF-like growth factor(PMID:15809022). It has 2 isoforms produced by alternative splicing.

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