Anticorps Recombinant de lapin anti-NRG1, isoform Alpha

NRG1, isoform Alpha Recombinant Antibody for IF/ICC, IF-P, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, IF-P, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240067A6

N° de cat : 83251-2-PBS

Synonymes

NRG1, NRG1A, 240067A6, ARIA, GGF

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Galerie de données de validation

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  IF Staining of rat brain using 83251-2-RR (same clone as 83251-2-PBS)

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded rat brain tissue using NRG1, isoform Alpha antibody (83251-2-RR, Clone: 240067A6 ) at dilution of 1:500 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 83251-2-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 83251-2-RR (same clone as 83251-2-PBS)

  Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using NRG1, isoform Alpha antibody (83251-2-RR, Clone: 240067A6 ) at dilution of 1:250 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 83251-2-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 83251-2-PBS

  Biolayer interferometry (BLl) kinetic assay of 83251-2-PBS against Human NRG1, isoform Alpha was performed. The affinity constant is 16.9 nM.

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Informations sur le produit

83251-2-PBS cible NRG1, isoform Alpha dans les applications de IF/ICC, IF-P, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: NRG1, isoform Alpha Protéine recombinante Ag35114
• Nom complet: neuregulin 1
• Masse moléculaire calculée: 70 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC007675
• Symbole du gène: NRG1
• Identification du gène (NCBI): 3084
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain. The immunogen of this antibody is against NRG1 isoform Alpha.

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