Anticorps Polyclonal de lapin anti-NRG1, isoform Alpha

NRG1, isoform Alpha Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31043-1-PBS

Synonymes

NRG1, NRG1A, ARIA, GGF, GGF2

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Galerie de données de validation

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  WB analysis using 31043-1-AP (same clone as 31043-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31043-1-AP (NRG1, isoform Alpha antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31043-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 31043-1-AP (same clone as 31043-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 31043-1-AP (NRG1, isoform Alpha antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31043-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 31043-1-AP (same clone as 31043-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 31043-1-AP (NRG1, isoform Alpha antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31043-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse stomach using 31043-1-AP (same clone as 31043-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 31043-1-AP (NRG1, isoform Alpha antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31043-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse stomach using 31043-1-AP (same clone as 31043-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 31043-1-AP (NRG1, isoform Alpha antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 31043-1-PBS in a different storage buffer formulation.

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  IF Staining of MCF-7 using 31043-1-AP (same clone as 31043-1-PBS)

  Immunofluorescent analysis of (-20°C Methanol) fixed MCF-7 cells using NRG1, isoform Alpha antibody (31043-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 31043-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31043-1-PBS cible NRG1, isoform Alpha dans les applications de WB, IHC, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NRG1, isoform Alpha Protéine recombinante Ag35114
• Nom complet: neuregulin 1
• Masse moléculaire calculée: 70 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC007675
• Symbole du gène: NRG1
• Identification du gène (NCBI): 3084
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Neuregulin 1 (NRG1) is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by usage of different promoters and alternative splicing of a single gene. NRG1 and its receptor ErbB tyrosine kinase are expressed not only in the developing nervous system, but also in the adult brain. The immunogen of this antibody is against NRG1 isoform Alpha.

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