Anticorps Polyclonal de lapin anti-NRG4

NRG4 Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27292-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 27292-1-AP (same clone as 27292-1-PBS)

  Recombinant human NRG4 protein Eg0997 was subjected to SDS PAGE followed by western blot with 27292-1-AP (NRG4 antibody) at dilution of 1:3000 and incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

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  IHC staining of human breast cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human breast cancer using 27292-1-AP (same clone as 27292-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 27292-1-AP (NRG4 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27292-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27292-1-PBS cible NRG4 dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NRG4 Protéine recombinante Ag26044
• Nom complet: neuregulin 4
• Masse moléculaire calculée: 13 kDa
• Numéro d’acquisition GenBank: BC017568
• Symbole du gène: NRG4
• Identification du gène (NCBI): 145957
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Neuregulin 4 (Nrg4), a member of the epidermal growth factor (EGF) family of extracellular ligands, is expressed in multiple organs with the highest expression levels in brown adipose tissue. Neuregulin 4 is a secreted adipokine recently identified as playing an important role in modulating systemic energy metabolism and in the development of metabolic disorders in rodent and human obesity, including type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Nrg4 attenuates hepatic lipogenic signaling and preserves glucose and lipid homeostasis in obesity.

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