- Phare
- Validé par KD/KO
Anticorps Monoclonal anti-Neuropilin 1/CD304
Neuropilin 1/CD304 Monoclonal Antibody for WB, IF/ICC, ELISA
Hôte / Isotype
Mouse / IgG1
Réactivité testée
Humain, Lapin, porc et plus (2)
Applications
WB, IF/ICC, IP, CoIP, ELISA
Conjugaison
Non conjugué
CloneNo.
2H3F6
N° de cat : 60067-1-Ig
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en WB | tissu placentaire humain, cellules A549, cellules HeLa, cellules MDA-MB-231, plasma humain, tissu cardiaque de lapin, tissu cardiaque de porc, tissu cérébral de porc, tissu cérébral humain fœtal |
| Résultats positifs en IF/ICC | cellules SH-SY5Y, cellules souches embryonnaires humaines |
Dilution recommandée
| Application | Dilution |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:6000 |
| Immunofluorescence (IF)/ICC | IF/ICC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| KD/KO | See 3 publications below |
| WB | See 15 publications below |
| IF | See 10 publications below |
| IP | See 2 publications below |
| CoIP | See 1 publications below |
Informations sur le produit
60067-1-Ig cible Neuropilin 1/CD304 dans les applications de WB, IF/ICC, IP, CoIP, ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc
| Réactivité | Humain, Lapin, porc |
| Réactivité citée | Humain, Lapin, souris, xénope |
| Hôte / Isotype | Mouse / IgG1 |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | Neuropilin 1/CD304 Protéine recombinante Ag0931 |
| Nom complet | neuropilin 1 |
| Masse moléculaire calculée | 103 kDa |
| Poids moléculaire observé | 130 kDa |
| Numéro d’acquisition GenBank | BC007737 |
| Symbole du gène | Neuropilin 1 |
| Identification du gène (NCBI) | 8829 |
| Conjugaison | Non conjugué |
| Forme | Liquide |
| Méthode de purification | Purification par protéine G |
| Tampon de stockage | PBS with 0.02% sodium azide and 50% glycerol |
| Conditions de stockage | Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA. |
Informations générales
Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.
Protocole
| Product Specific Protocols | |
|---|---|
| WB protocol for Neuropilin 1/CD304 antibody 60067-1-Ig | Download protocol |
| IF protocol for Neuropilin 1/CD304 antibody 60067-1-Ig | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Elife Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons. | ||
Acta Biomater Semaphorin-3A, Neuropilin-1 and Plexin-A1 in Prosthetic-Particle Induced Bone Loss. | ||
J Pathol Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma. | ||
Am J Cancer Res CMTM6 promotes cell proliferation and invasion in oral squamous cell carcinoma by interacting with NRP1. | ||
Pharm Res Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy. | ||
Exp Eye Res Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injury. |










