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Anticorps Monoclonal anti-Neuropilin 1/CD304

Neuropilin 1/CD304 Monoclonal Antibody for WB, IF/ICC, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, Lapin, porc et plus (2)

Applications

WB, IF/ICC, IP, CoIP, ELISA

Conjugaison

Non conjugué

Publications(26)

CloneNo.

2H3F6

N° de cat : 60067-1-Ig

Synonymes

Neuropilin 1, NRP1, 2H3F6, BDCA4, CD304



Applications testées

Résultats positifs en WBtissu placentaire humain, cellules A549, cellules HeLa, cellules MDA-MB-231, plasma humain, tissu cardiaque de lapin, tissu cardiaque de porc, tissu cérébral de porc, tissu cérébral humain fœtal
Résultats positifs en IF/ICCcellules SH-SY5Y, cellules souches embryonnaires humaines

Dilution recommandée

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:6000
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

60067-1-Ig cible Neuropilin 1/CD304 dans les applications de WB, IF/ICC, IP, CoIP, ELISA et montre une réactivité avec des échantillons Humain, Lapin, porc

Réactivité Humain, Lapin, porc
Réactivité citéeHumain, Lapin, souris, xénope
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène Neuropilin 1/CD304 Protéine recombinante Ag0931
Nom complet neuropilin 1
Masse moléculaire calculée 103 kDa
Poids moléculaire observé 130 kDa
Numéro d’acquisition GenBankBC007737
Symbole du gène Neuropilin 1
Identification du gène (NCBI) 8829
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS with 0.02% sodium azide and 50% glycerol
Conditions de stockageStocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Neuropilin-1 (NRP1) is a 130-140 kDa transmembrane glycoprotein expressed by endothelial, dendritic, and regulatory T cells, as well as several other normal cell types and malignant tumor cells. NRP1 was first identified as a semaphorin (SEMA) receptor, involved in axonal guidance in embryonic development. NRP1 was also shown to act as a receptor for vascular endothelial growth factor (VEGF) and a promoter of angiogenesis through its interaction with VEGF-A165 (and other VEGFs) and the receptor tyrosine kinase (RTK) VEGF-R2. NRP1 plays versatile roles in angiogenesis, axon guidance, cell survival, migration, and invasion.

Protocole

Product Specific Protocols
WB protocol for Neuropilin 1/CD304 antibody 60067-1-IgDownload protocol
IF protocol for Neuropilin 1/CD304 antibody 60067-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
XenopusIF

Elife

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons.

Authors - Max Koppers
humanIF

Acta Biomater

Semaphorin-3A, Neuropilin-1 and Plexin-A1 in Prosthetic-Particle Induced Bone Loss.

Authors - S Saad
human

J Pathol

Perivascular Neuropilin-1 expression is an independent marker of improved survival in renal cell carcinoma.

Authors - Eric Morin
humanIF

Am J Cancer Res

CMTM6 promotes cell proliferation and invasion in oral squamous cell carcinoma by interacting with NRP1.

Authors - Yang Zheng
mouseWB

Pharm Res

Dual Receptor Targeting Cell Penetrating Peptide Modified Liposome for Glioma and Breast Cancer Postoperative Recurrence Therapy.

Authors - Yue Qiu
mouseIF

Exp Eye Res

Expression of axon guidance ligands and their receptors in the cornea and trigeminal ganglia and their recovery after corneal epithelium injury.

Authors - Victor H Guaiquil
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