Anticorps Monoclonal anti-NSUN6

NSUN6 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, porc

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1H1H8

N° de cat : 68614-1-PBS

Synonymes

4933414E04Rik, FLJ23743, NOPD1, NSUN6

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Galerie de données de validation

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  WB analysis using 68614-1-Ig (same clone as 68614-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68614-1-Ig (NSUN6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68614-1-PBS in a different storage buffer formulation.

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Informations sur le produit

68614-1-PBS cible NSUN6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc

• Réactivité: Humain, porc
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: NSUN6 Protéine recombinante Ag11084
• Nom complet: NOL1/NOP2/Sun domain family, member 6
• Masse moléculaire calculée: 469 aa, 52 kDa
• Poids moléculaire observé: 50-52 kDa
• Numéro d’acquisition GenBank: BC035778
• Symbole du gène: NSUN6
• Identification du gène (NCBI): 221078
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NSUN6 is an RNA methyltransferase that catalyzes the methylation at position cytosine C72 in some tRNAs. NSUN6 has been reported to localize to the cytoplasm and largely colocalize with the Golgi apparatus and pericentriolar matrix, indicating that NSUN6 modifies tRNAs in a late step in their biogenesis. NSUN6 may also play a major role in bone metastasis and could be a valuable therapeutic target for bone metastasis.

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