Anticorps Polyclonal de lapin anti-NSUN7

NSUN7 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17546-1-PBS

Synonymes

FLJ14001

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Galerie de données de validation

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  WB analysis using 17546-1-AP (same clone as 17546-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17546-1-AP (NSUN7 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17546-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 17546-1-AP (same clone as 17546-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17546-1-AP (NSUN7 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17546-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat testis using 17546-1-AP (same clone as 17546-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat testis tissue slide using 17546-1-AP (NSUN7 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17546-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17546-1-PBS cible NSUN7 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NSUN7 Protéine recombinante Ag11650
• Nom complet: NOL1/NOP2/Sun domain family, member 7
• Masse moléculaire calculée: 718 aa, 81 kDa
• Poids moléculaire observé: 80 kDa
• Numéro d’acquisition GenBank: BC036568
• Symbole du gène: NSUN7
• Identification du gène (NCBI): 79730
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NSUN7 (NOP2/Sun RNA methyltransferase family member 7) is involved in mitochondrial rRNA processing in post-meiotic sperm and is predicted to act upstream of or within flagellated sperm motility and sperm mitochondrion organization. In humans, Nsun7 encodes a protein with 718-amino acid and 3697-bp belonging to the methyltransferase superfamily (PMID: 37173708). The failure to produce NSUN7 would lead to the impairment in activity and motility of sperm flagella, leading to sperm motility deficit and infertility (PMID: 25702163).

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