Anticorps Polyclonal de lapin anti-NT5DC2

NT5DC2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31739-1-PBS

Synonymes

5'-nucleotidase domain-containing protein 2, EC:3.1.3.-

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Galerie de données de validation

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  WB analysis using 31739-1-AP (same clone as 31739-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31739-1-AP (NT5DC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31739-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31739-1-PBS cible NT5DC2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NT5DC2 Protéine recombinante Ag35015
• Nom complet: 5'-nucleotidase domain containing 2
• Masse moléculaire calculée: 61 kDa
• Poids moléculaire observé: 60-65 kDa
• Numéro d’acquisition GenBank: NM_022908
• Symbole du gène: NT5DC2
• Identification du gène (NCBI): 64943
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

5'-Nucleotidase domain containing 2 (NT5DC2) is a member of the NT5DC family and contains a haloacid dehalogenase motif localized in the N-terminus of these proteins (PMID: 32962856). NT5DC2 is associated with attention-deficit/hyperactivity disorder and bipolar disorder. NT5DC2 has been shown to interact with and stabilize Fyn, a Src family proto-oncogene, and plays a role in regulating glioblastoma progression. NT5DC2 promotes tumor cell proliferation by stabilizing EGFR in hepatocellular carcinoma (PMID: 32382041).

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