Anticorps Recombinant de lapin anti-NTB-A/SLAMF6

NTB-A/SLAMF6 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241384G5

N° de cat : 84211-4-PBS

Synonymes

SLAMF6, Ly108, KALIb, KALI, CD352

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Galerie de données de validation

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  WB analysis using 84211-4-RR (same clone as 84211-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84211-4-RR (NTB-A/SLAMF6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84211-4-PBS in a different storage buffer formulation.

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  IF Staining of Ramos using 84211-4-RR (same clone as 84211-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed Ramos cells using NTB-A/SLAMF6 antibody (84211-4-RR, Clone: 241384G5 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84211-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84211-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84211-4-RR against Human NTB-A/SLAMF6 were performed. The affinity constant is 2.73 nM.

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Informations sur le produit

84211-4-PBS cible NTB-A/SLAMF6 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: SLAM family member 6
• Masse moléculaire calculée: 37kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: NM_001184714.2
• Symbole du gène: SLAMF6
• Identification du gène (NCBI): 114836
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Signaling lymphocyte activation molecule 6 (SLAMF6) (Ly108 in mice, NTB-A or SF2000 in humans) is a homophilic receptor belonging to the superfamily immunoglobulin (Ig) domain-containing molecules (PMID:31199820). SLAMF6 is a type I transmembrane protein with two extracellular immunoglobins (Ig)-like domains and three cytoplasmic tyrosine-based signaling motifs, one of which is immunoreceptor tyrosine-based switch motif (PMID:31315913). SLAMF6 is expressed on a wide variety of immune cells including T cells (also TFH), B cells, NK cells (expressed in humans only), double positive thymocytes, eosinophils, and neutrophils (mouse only) (PMID:11862385).

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