Anticorps Polyclonal de lapin anti-NTN3

NTN3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 31893-1-PBS

Synonymes

NTN2L, Netrin-3, Netrin-2-like protein, netrin 3, Netrin 2 like protein

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Galerie de données de validation

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  WB analysis using 31893-1-AP (same clone as 31893-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 31893-1-AP (NTN3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31893-1-PBS in a different storage buffer formulation.

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Informations sur le produit

31893-1-PBS cible NTN3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: NTN3 Protéine recombinante Ag34435
• Nom complet: netrin 3
• Masse moléculaire calculée: 61 kDa
• Poids moléculaire observé: 62-70 kDa
• Numéro d’acquisition GenBank: Netrin-3
• Symbole du gène: NTN3
• Identification du gène (NCBI): 4917
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

NTN3 (Netrin-3), also known as NTN2L. NTN3 (Netrin-3) is predicted to be located in the Golgi apparatus and extracellular region, and it is also predicted to be active in the basement membrane. It is detected in various amounts in the skin, esophagus, bronchus, nasal cavity, kidney, and vagina in healthy human tissues (PMID: 37345154). The protein is predicted to enable signaling receptor binding activity and is involved in animal organ morphogenesis, neuron projection development, and tissue development. Netrins, including NTN3, are a group of proteins that exhibit structural homology to the extracellular matrix protein laminin and influence neurological and tumor progression. NTN3, along with other netrin family members, may play a role in tumor growth and migration in specific organs where they are expressed, potentially affecting disease progression. However, further research is needed to elucidate the precise prognostic and biological implications of NTN3 in various diseases, including cancer (PMID: 32251318). The molecular weight of NTN3 is 62 kDa. It is possible that the protein has glycosylation modification.

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