Anticorps Monoclonal anti-TrkA

TrkA Monoclonal Antibody for WB, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, ELISA

Conjugaison

Non conjugué

CloneNo.

3B11C7

N° de cat : 60548-1-Ig

Synonymes

NTRK1, Trk A, TRK, p140 TrkA, MTC

---

Galerie de données de validation

• 

  WB analysis using 60548-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of NK-92 using 60548-1-Ig

  NK-92 cells were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 60548-1-Ig

  Various lysates were subjected to SDS PAGE followed by western blot with 60548-1-Ig (NTRK1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: Karpas-299 cells, cellules K-562, cellules MOLT-4, cellules SH-SY5Y, cellules TF-1

Dilution recommandée

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

60548-1-Ig cible TrkA dans les applications de WB, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: TrkA Protéine recombinante Ag27985
• Nom complet: neurotrophic tyrosine kinase, receptor, type 1
• Masse moléculaire calculée: 88 kDa
• Poids moléculaire observé: 140 kDa
• Numéro d’acquisition GenBank: NM_001007792
• Symbole du gène: NTRK1
• Identification du gène (NCBI): 4914
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

NTRK1(Neurotrophic tyrosine kinase receptor 1) is located on chromosome 1q23.1 and is responsible for a rare genetic disorder, CIPA (congenital insensitivity to pain with anhidrosis) (PMID: 37907480). As a neurotrophin receptor, NTRK1 is abundantly expressed in human neuronal tissues and plays an integral role in the development and function of the human nervous system (PMID: 27843590). NTRK1 also regulates the survival and proliferation of cholinergic neurons (PMID: 20054812).

{{ptg:RelatedPrimaryAntibodies}}