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Anticorps Recombinant de lapin anti-Nectin-2/CD112

Nectin-2/CD112 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241798A11

N° de cat : 84439-6-PBS

Synonymes

241798A11, CD112, Herpes virus entry mediator B, HveB, mHveB

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of various lysates using Nectin-2/CD112 Recombinant antibody (84439-6-RR)

    WB analysis using 84439-6-RR (same clone as 84439-6-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84439-6-RR (Nectin-2/CD112 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84439-6-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of RAW 264.7 cells using Nectin-2/CD112 Recombinant antibody (84439-6-RR)

    IF Staining of RAW 264.7 using 84439-6-RR (same clone as 84439-6-PBS)

    Immunofluorescent analysis of (4% PFA) fixed RAW 264.7 cells using Nectin-2/CD112 antibody (84439-6-RR, Clone: 241798A11 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84439-6-PBS in a different storage buffer formulation.

Informations sur le produit

84439-6-PBS cible Nectin-2/CD112 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons souris

Réactivité souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Nectin-2/CD112 Protéine recombinante Eg2019
Nom complet poliovirus receptor-related 2
Masse moléculaire calculée57 kDa
Poids moléculaire observé65-75 kDa
Numéro d’acquisition GenBankNM_008990.3
Symbole du gène Nectin-2/CD112
Identification du gène (NCBI) 19294
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Nectin 2, also named as PVRL2, CD112, HVEB, PRR2 and PVRR2, is an adhesion molecule widely expressed in cell lines of different lineages, including hematopoietic, neuronal, endothelial and epithelial cells. CD112 belongs to a new family of immunoglobulin-like molecules that includes four members (CD111, CD112, PRR3 and CD155) sharing an ectodomain made of three Ig domains, of V and C types. CD112 is expressed in the myelo-monocytic and megakaryocytic hematopoietic lineages and the function in hematopoiesis is currently unknown. CD112 is an intercellular homophilic adhesion. CD112 localizes specifically at adherents junctions via its cytoplasmic interaction with the scaffold F-actin binding protein afadin. Disruption of the murine CD112 gene leads to infertility of male mice with morphologically aberrant spermatozoa. CD112 mediates entry of some alphaherpesvirus mutants (also named HveB) via its V domain. CD112 is involved in cell to cell spreading of viruses.

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