Anticorps Monoclonal anti-Nephrin

Nephrin Monoclonal Antibody for IHC, ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

IHC, ELISA

Conjugaison

Non conjugué

CloneNo.

1D11H8

N° de cat : 66970-1-PBS

Synonymes

NPHS1, 1D11H8, CNF, NPHN, NPHS 1

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Galerie de données de validation

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  IHC staining of human kidney using 66970-1-Ig (same clone as 66970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66970-1-Ig (Nephrin antibody) at dilution of 1:4000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66970-1-PBS in a different storage buffer formulation.

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  IHC staining of human kidney using 66970-1-Ig (same clone as 66970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66970-1-Ig (Nephrin antibody) at dilution of 1:4000 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66970-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66970-1-PBS cible Nephrin dans les applications de IHC, ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Nephrin Protéine recombinante Ag19273
• Nom complet: nephrosis 1, congenital, Finnish type (nephrin)
• Masse moléculaire calculée: 1241 aa, 135 kDa
• Numéro d’acquisition GenBank: BC156935
• Symbole du gène: Nephrin
• Identification du gène (NCBI): 4868
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Podocytes are a major component of the glomerular blood filtration barrier. Podocyte protein Nephrin, also known as NPHS1, is the first to be identified as a central component of the slit diaphragm (SD), which is podocyte cell-cell junction. Mutations in Nephrin lead to congenital nephrosis, such as steroid-resistant proteinuria and congenital nephrotic syndrome of the Finnish type (CNF).

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