Anticorps Recombinant de lapin anti-Neuropilin 1/CD304

Neuropilin 1/CD304 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241812B11

N° de cat : 98210-1-PBS

Synonymes

neuropilin 1, NRP1, Neuropilin-1, CD304, BDCA4

---

Galerie de données de validation

• 

  FC experiment of HUVEC using 98210-1-RR (same clone as 98210-1-PBS)

  1x10^6 HUVEC cells (left) or MCF-7 cells (right) were surface stained with 0.25 ug Anti-Human Neuropilin 1/CD304 Rabbit Recombinant Antibody (98210-1-RR, Clone: 241812B11) (red) or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98210-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

98210-1-PBS cible Neuropilin 1/CD304 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: neuropilin 1
• Numéro d’acquisition GenBank: BC007533
• Symbole du gène: Neuropilin 1
• Identification du gène (NCBI): 8829
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Neuropilin 1 (NRP1), also known as CD304 or VEGF165R, is a type I transmembrane proteins consisting of a small intracellular cytoplasmic domain, a transmembrane domain and an extracellular domain containing a complement-binding CUB domain (a1/a2), a coagulation factor V/VIII (b1/b2) domain, and a meprin or MAM domain (PMID: 24263240; 11886873). It is expressed on plasmacytoid dendritic cells (pDCs), endothelial cells, thymocytes, regulatory T cells, a subset of T follicular helper cells, neurons, and diverse human solid tumors (PMID: 31944572; 14991591; 18704117). Neuropilin 1 is involved in immunity, cardiovascular development, neuronal guidance, cell migration, angiogenesis and cancer pathogenesis (PMID: 24263240).

{{ptg:RelatedPrimaryAntibodies}}