Anticorps Monoclonal anti-NeutraControl PDGF-BB

NeutraControl PDGF-BB Monoclonal Antibody for Non-Neutralization, ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

Non-Neutralization, ELISA

Conjugaison

Non conjugué

CloneNo.

4E2C7

N° de cat : 69520-1-Ig

Synonymes

Becaplermin, c sis, FLJ12858, PDGF 2, PDGF subunit B, PDGF2, PDGFB, Proto oncogene c Sis, SIS, SSV



Applications publiées

ELISASee 1 publications below

Informations sur le produit

69520-1-Ig cible PDGF-BB dans les applications de Non-Neutralization, ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Réactivité citéeHumain
Hôte / Isotype Mouse / IgG2a
Clonalité Monoclonal
Type Anticorps
Immunogène human Humankine PDGF-BB protein HZ-1308
Nom complet platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)
Symbole du gène PDGFB
Identification du gène (NCBI) 5155
Conjugaison Non conjugué
Forme Lyophilized Powder
Méthode de purification Purification par protéine A
Tampon de stockage PBS stérile.
Endotoxin<0.1 EU/μg
ReconstitutionThis product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use.
Stability and StorageLyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products.

Informations générales

Platelet-derived growth factor (PDGF) belongs to the family of growth factors consisting of four secreted extracellular ligands including PDGF-A, -B, -C and -D. These isoforms, PDGF-AA, PDGF-AB, PDGF-BB, PDGF-CC and PDGF-DD, act via two receptor tyrosine kinases, PDGF receptors alpha and beta. PDGF isoforms stimulate growth, survival and motility of mesenchymal cells and certain other cell type. They have important functions during embryonal development and in the control of tissue homeostasis in the adult. PDGF-BB is one of the most recently studied isoforms and it plays an important role in skeletal development. PDGF-BB stimulates cell-mediated collagen gel contraction. PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors.

This antibody is a neutralizing control antibody for PDGF-BB, the immunogen is the same as Neutrakine 69020-1-Ig but could not neutralize human PDGF-BB.

Publications

SpeciesApplicationTitle
humanELISA

Free Radic Biol Med

IRF1/ZNF350/GPX4-mediated ferroptosis of renal tubular epithelial cells promote chronic renal allograft interstitial fibrosis

Authors - Yao Zhang