Anticorps Recombinant de lapin anti-OAS2

OAS2 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242801F11

N° de cat : 82758-2-PBS

Synonymes

EC:2.7.7.84, 2'-5'-oligoadenylate synthase 2, 2-5A synthase 2, 242801F11, (2-5')oligo(A) synthase 2

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Galerie de données de validation

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  WB analysis using 82758-2-RR (same clone as 82758-2-PBS)

  IFN alpha treated A549 cells were subjected to SDS PAGE followed by western blot with 82758-2-RR (OAS2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82758-2-PBS in a different storage buffer formulation.

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  WB analysis using 82758-2-RR (same clone as 82758-2-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 82758-2-RR (OAS2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82758-2-PBS in a different storage buffer formulation.

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Informations sur le produit

82758-2-PBS cible OAS2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: OAS2 Protéine recombinante Ag6170
• Nom complet: 2'-5'-oligoadenylate synthetase 2, 69/71kDa
• Masse moléculaire calculée: 82 kDa
• Poids moléculaire observé: 66-71 kDa
• Numéro d’acquisition GenBank: BC049215
• Symbole du gène: OAS2
• Identification du gène (NCBI): 4939
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The 2-prime,5-prime oligoadenylate synthetases (OASs), such as OAS2, are IFN-induced proteins characterized by their capacity to catalyze the synthesis of 2-prime,5-prime oligomers of adenosine (2-5As). OAS2 is also named as p69 OAS / p71 OAS. It has 3 isoforms(71/69/20 kDa) produced by alternative splicing. The OAS2 isozymes are 69-71 kDa and form dimers(PMID:17765707). Glycosylation is essential for its activity(PMID:9880569). Constitutive expression of the 69-kDa form of the OAS2 protein in human cells inhibited the replication of encephalomyocarditis virus (EMCV) but not that of VSV, Sendai virus, or reovirus(PMID:16501108).

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