Anticorps Monoclonal anti-OCIAD1

• Phare
• Validé par KD/KO

OCIAD1 Monoclonal Antibody for IF/ICC, IF-P

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, rat, souris

Applications

IF/ICC, IF-P

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

1C10C3

N° de cat : CL488-66698

Synonymes

Ovarian cancer immunoreactive antigen domain containing 1, OCIA domain-containing protein 1, OCIA domain containing 1, OCIA, ASRIJ

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Galerie de données de validation

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  IF Staining of human liver cancer using CL488-66698

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 OCIAD1 antibody (CL488-66698, Clone: 1C10C3 ) at dilution of 1:200.

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  IF Staining of human liver cancer using CL488-66698

  Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite® Plus 488 OCIAD1 antibody (CL488-66698, Clone: 1C10C3 ) at dilution of 1:200.

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  IF Staining of HeLa using CL488-66698

  Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite® Plus 488 OCIAD1 antibody (CL488-66698, Clone: 1C10C3 ) at dilution of 1:200.

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Applications testées

• Résultats positifs en IF-P: tissu de cancer du foie humain,
• Résultats positifs en IF/ICC: cellules HeLa,

Dilution recommandée

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500
• Immunofluorescence (IF)/ICC: IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-66698 cible OCIAD1 dans les applications de IF/ICC, IF-P et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: OCIAD1 Protéine recombinante Ag9977
• Nom complet: OCIA domain containing 1
• Masse moléculaire calculée: 28 kDa
• Poids moléculaire observé: 35 kDa
• Numéro d’acquisition GenBank: BC003409
• Symbole du gène: OCIAD1
• Identification du gène (NCBI): 54940
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 493 nm / 522 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Conditions de stockage: Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

OCIAD1 was first identified by immunoscreening of an ovarian carcinoma cDNA expression library with ascites fluid from ovarian cancer patients (PMID: 11162530). OCIAD1 has been reported as a key player in ovarian cancer cell adhesion, as well as a key player in generating ovarian cancer recurrence (PMID: 18328549; 20515946). In addition to its roles in cancer, OCIAD1 participates in maintaining stem cell potency by regulating the Jak/STAT pathway (PMID: 23972987). Several alternatively spliced forms of OCIAD1 gene have been identified. The longest form (1.4 kb) is predicted to encode for a 27.6 kDa protein of 245 amino acids. This antibody detects OCIAD1 with an apparent molecular weight of ~35 kDa as has been demonstrated by several researches (PMID: 27345969; 27345976).

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