Anticorps Polyclonal de lapin anti-OIT3

OIT3 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32301-1-PBS

Synonymes

Liver-specific zona pellucida domain-containing protein, LZP, Oncoprotein-induced transcript 3 protein, UNQ826/PRO1753

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Galerie de données de validation

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  WB analysis using 32301-1-AP (same clone as 32301-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32301-1-AP (OIT3 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32301-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32301-1-PBS cible OIT3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: OIT3 Protéine recombinante Ag36932
• Nom complet: oncoprotein induced transcript 3
• Masse moléculaire calculée: 60 kDa，545aa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: NM_152635.2
• Symbole du gène: OIT3
• Identification du gène (NCBI): 170392
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Oncoprotein-induced transcript 3 protein (OIT3) is a liver-specific protein. It is involved in various biological processes, including lipid metabolism and ferroptosis regulation. OIT3 has been shown to mediate macrophage polarization and facilitate hepatocellular carcinoma (HCC) progression by regulating the arachidonic acid metabolism and reactive oxygen species (ROS) accumulation (PMID: 35353239). Additionally, OIT3 is implicated in the regulation of lipid metabolism, particularly in the context of triacylglycerol and very low-density lipoproteins (VLDLs) in the liver (PMID: 36132142).

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