Anticorps Polyclonal de lapin anti-OLAH

OLAH Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 17676-1-PBS

Synonymes

Augmented in rheumatoid arthritis 1, AURA1, EC:3.1.2.14, Oleoyl-ACP hydrolase, S-acyl fatty acid synthase thioesterase, medium chain

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Galerie de données de validation

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  WB analysis using 17676-1-AP (same clone as 17676-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 17676-1-AP (OLAH antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17676-1-PBS in a different storage buffer formulation.

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  WB analysis using 17676-1-AP (same clone as 17676-1-PBS)

  MCF-10A cells were subjected to SDS PAGE followed by western blot with 17676-1-AP (OLAH antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17676-1-PBS in a different storage buffer formulation.

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Informations sur le produit

17676-1-PBS cible OLAH dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: OLAH Protéine recombinante Ag11694
• Nom complet: oleoyl-ACP hydrolase
• Masse moléculaire calculée: 265 aa, 30 kDa
• Poids moléculaire observé: 36 kDa
• Numéro d’acquisition GenBank: BC050372
• Symbole du gène: OLAH
• Identification du gène (NCBI): 55301
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

OLAH protein, also known as oleoyl-ACP hydrolase, is an enzyme involved in fatty acid production. It has been found to play a role in various biological processes and diseases. For instance, placental OLAH levels are altered in fetal growth restriction and preeclampsia, suggesting its potential involvement in placental dysfunction. Additionally, OLAH has been linked to severe respiratory diseases, where it mediates life-threatening inflammation associated with viral infections. Its expression is also associated with fatal outcomes in certain viral infections. These findings highlight the importance of OLAH in both reproductive health and infectious diseases (PMID: 36139751, PMID: 39137778, PMID: 39178832). OLAH has two isoforms with molecular masses of 30 kDa and 36 kDa.

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