Anticorps Recombinant de lapin anti-OLR1/LOX1

OLR1/LOX1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250525B12

N° de cat : 98524-3-RR

Synonymes

OLR1, CLEC8A, C-type lectin domain family 8 member A, hLOX 1, hLOX1

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Galerie de données de validation

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  FC experiment of human PBMCs using 98524-3-RR

  1x10^6 untreated or GM-CSF-treated human PBMCs were surface stained with 0.25 ug Anti-Human OLR1/LOX1 Rabbit RecAb (98524-3-RR, Clone: 250525B12) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD14. Cells were not fixed. Monocytes were gated.

• 

  FC experiment of human PBMCs using 98524-3-RR

  1x10^6 GM-CSF-treated human PBMCs were surface stained with 0.25 ug Anti-Human OLR1/LOX1 Rabbit RecAb (98524-3-RR, Clone: 250525B12) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). 1x10^6 untreated human PBMCs were surface stained with 0.25 ug Anti-Human OLR1/LOX1 Rabbit RecAb (98524-3-RR, Clone: 250525B12) (black, dashed) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Monocytes were gated.

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Applications testées

• Résultats positifs en cytométrie: GM-CSF treated human PBMCs,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98524-3-RR cible OLR1/LOX1 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: OLR1/LOX1 Protéine recombinante Eg2911
• Nom complet: oxidized low density lipoprotein (lectin-like) receptor 1
• Masse moléculaire calculée: 31 kDa
• Numéro d’acquisition GenBank: NM_002543.3
• Symbole du gène: OLR1
• Identification du gène (NCBI): 4973
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

OLR1/LOX-1 acts as a receptor, in the form of homodimer, that mediates the recognition, internalization, and degradation of oxidatively modified low density lipoprotein (oxLDL) (PMID: 9052782, 15695803). ORL1 is predominantly expressed in endothelial cells and vascular-rich organs such as the placenta, lung, liver, and brain (PMID: 9828121). OLR1 is a protein containing 273 amino acids with a calculated molecular mass of 31 kDa but an apparent molecular mass of 50 kDa, which may result from the glycosylation of four potential N-linked glycosylation sites located at the C-terminal domain (PMID: 9052782).

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