Anticorps Monoclonal anti-OMA1

OMA1 Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain, souris

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1H4D12

N° de cat : 67449-1-PBS

Synonymes

Overlapping with the m-AAA protease 1 homolog, MPRP-1, MPRP1, Metalloprotease-related protein 1, EC:3.4.24.-

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Galerie de données de validation

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  WB analysis of NIH/3T3 using 67449-1-Ig (same clone as 67449-1-PBS)

  NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 67449-1-Ig (OMA1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67449-1-PBS in a different storage buffer formulation.

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  WB analysis using 67449-1-Ig (same clone as 67449-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67449-1-Ig (OMA1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67449-1-PBS in a different storage buffer formulation.

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  WB analysis of Jurkat using 67449-1-Ig (same clone as 67449-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 67449-1-Ig (OMA1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67449-1-PBS in a different storage buffer formulation.

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  WB analysis of HeLa using 67449-1-Ig (same clone as 67449-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 67449-1-Ig (OMA1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67449-1-PBS in a different storage buffer formulation.

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  WB analysis of LNCaP using 67449-1-Ig (same clone as 67449-1-PBS)

  LNCaP cells were subjected to SDS PAGE followed by western blot with 67449-1-Ig (OMA1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67449-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50571-3

  Cytometric bead array standard curve of MP50571-3, OMA1 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 66572-1-PBS. Detection antibody: 67449-1-PBS. Standard:Ag11201. Range: 3.125-100 ng/mL.

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Informations sur le produit

67449-1-PBS cible OMA1 dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: OMA1 Protéine recombinante Ag11201
• Nom complet: OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
• Masse moléculaire calculée: 524 aa, 60 kDa
• Poids moléculaire observé: 60 kDa
• Numéro d’acquisition GenBank: BC012915
• Symbole du gène: OMA1
• Identification du gène (NCBI): 115209
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

OMA1(Overlapping with the m-AAA protease 1 homolog) is also named as MPRP1(Metalloprotease-related protein 1) and belongs to the peptidase M48 family.It is a zinc metalloprotease that spans the inner mitochondrial membrane with a number of predicted membrane spanning domains and the 60 kDa form of OMA1 rapidly accumulated concomitantly with the cleavage of all OPA1 variants,and the 40 kDa form of OMA1 may be the inactive form, with the 60 kDa form being the active enzyme(PMID:20334834)

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