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Anticorps Polyclonal de lapin anti-OPN4

OPN4 Polyclonal Antibody for IF-P, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

IF-P, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 24478-1-PBS

Synonymes

Galerie de données de validation

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  • Immunofluorescence (IF) / fluorescent staining of mouse eye tissue using OPN4 Polyclonal antibody (24478-1-AP)

    IF Staining of mouse eye using 24478-1-AP (same clone as 24478-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using OPN4 antibody (24478-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24478-1-PBS in a different storage buffer formulation.

Informations sur le produit

24478-1-PBS cible OPN4 dans les applications de IF-P, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène OPN4 Protéine recombinante Ag21643
Nom complet opsin 4
Masse moléculaire calculée 478 aa, 53 kDa
Numéro d’acquisition GenBankBC113558
Symbole du gène OPN4
Identification du gène (NCBI) 94233
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

OPN4, an opsin that was first isolated from the skin of Xenopus laevis in 1998, belongs not to the vertebrate-type opsin family but rather to the invertebrate-type opsins, which are part of the seven-transmembrane G protein-coupled receptor (GPCR) family (PMID:31989708). In humans, OPN4 is expressed in the retinal ganglion cells in addition to part of the brain (PMID:10632589). Moreover, Opn4 functions as a photoreceptor by detecting brightness levels and discriminating visual signals (PMID:22633808). Opn4 also facilitates visual circuits to acquire optimal settings and light adaptation by measuring irradiance levels (PMID:25517373).

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