Anticorps Polyclonal de lapin anti-OPRL1

• Phare
• Validé par KD/KO

OPRL1 Polyclonal Antibody for WB, IHC, IP, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12970-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis of HeLa using 12970-1-AP (same clone as 12970-1-PBS)

  HeLa cells were subjected to SDS PAGE followed by western blot with 12970-1-AP (OPRL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

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  WB analysis of SH-SY5Y using 12970-1-AP (same clone as 12970-1-PBS)

  SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 12970-1-AP (OPRL1 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

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  IP experiment of SH-SY5Y using 12970-1-AP (same clone as 12970-1-PBS)

  IP result of anti-OPRL1 (IP:12970-1-AP, 4ug; Detection:12970-1-AP 1:500) with SH-SY5Y cells lysate 2000ug. This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 12970-1-AP (same clone as 12970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas using 12970-1-AP (OPRL1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

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  IHC staining of human gliomas using 12970-1-AP (same clone as 12970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human gliomas using 12970-1-AP (OPRL1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 12970-1-AP (same clone as 12970-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 12970-1-AP (OPRL1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12970-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12970-1-PBS cible OPRL1 dans les applications de WB, IHC, IP, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: OPRL1 Protéine recombinante Ag4079
• Nom complet: opiate receptor-like 1
• Masse moléculaire calculée: 370 aa, 41 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC038433
• Symbole du gène: OPRL1
• Identification du gène (NCBI): 4987
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The OPRL1 (opioid related nociceptin receptor 1) is the G-protein coupled receptor activated by the endogenou NC (neuropeptide nociceptin) (PMID:7566152). OPRL1 is widely expressed in the central nervous system, including the hippocampal dentate gyrus, cortical areas, striatum, thalamus, and hypothalamus (PMID:19501074). OPRL1 has been found to play an essential role in cognition, and to modulate inflammation and immune responses (PMID:30152845).

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