Anticorps Polyclonal de lapin anti-OPRM1

OPRM1 Polyclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 27625-1-PBS

Synonymes

MOR, MOP, M OR 1, LMOR, KIAA0403

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Galerie de données de validation

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  WB analysis using 27625-1-AP (same clone as 27625-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 27625-1-AP (OPRM1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27625-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 27625-1-AP (same clone as 27625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 27625-1-AP (OPRM1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27625-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 27625-1-AP (same clone as 27625-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 27625-1-AP (OPRM1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 27625-1-PBS in a different storage buffer formulation.

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Informations sur le produit

27625-1-PBS cible OPRM1 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: OPRM1 Protéine recombinante Ag24806
• Nom complet: opioid receptor, mu 1
• Masse moléculaire calculée: 45 kDa
• Poids moléculaire observé: 65-70 kDa
• Numéro d’acquisition GenBank: BC074927
• Symbole du gène: OPRM1
• Identification du gène (NCBI): 4988
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

OPRM1 (also known as Mu opioid receptor, MOR1, MOP) is a G protein-coupled receptor that mediates the physiological effects of endogenous opioids as well as the structurally distinct opioid alkaloids including morphine and etorphine (PMID: 9618555). Mu opioid receptor modulates a wide range of physiological functions, particularly involved in the control of pain perception and reward properties (PMID: 30483121). Mu opioid receptor is the principal target of opioid drugs. It is encoded by OPRM1 gene and multiple transcript variants encoding different isoforms have been found. Mu opioid receptor contains sites for N-linked glycosylation. The transcript variants and variations of glycosylation may result in migrating bands of Mu opioid receptor (PMID: 21886594; 11359768).

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