Anticorps Monoclonal anti-ORAI1

ORAI1 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain, porc, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3C12F9

N° de cat : 66223-1-PBS

Synonymes

ORAI1-L2, Orail-L2, 3C12F9, Calcium release-activated calcium channel protein 1, CRACM1

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Galerie de données de validation

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  WB analysis using 66223-1-Ig (same clone as 66223-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66223-1-Ig (ORAI1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66223-1-PBS in a different storage buffer formulation.

• 

  WB analysis using 66223-1-Ig (same clone as 66223-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 66223-1-Ig (ORAI1 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66223-1-PBS in a different storage buffer formulation.

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  WB analysis of A375 using 66223-1-Ig (same clone as 66223-1-PBS)

  A375 cells were subjected to SDS PAGE followed by western blot with 66223-1-Ig (ORAI1 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66223-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66223-1-PBS cible ORAI1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, porc, rat, souris

• Réactivité: Humain, porc, rat, souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: ORAI1 Protéine recombinante Ag18050
• Nom complet: ORAI calcium release-activated calcium modulator 1
• Masse moléculaire calculée: 301 aa, 33 kDa
• Poids moléculaire observé: 32 kDa
• Numéro d’acquisition GenBank: BC015369
• Symbole du gène: ORAI1
• Identification du gène (NCBI): 84876
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a 32-55 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed immunodeficiency (SCID) syndrome possess point mutations in Orai1 gene.

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