Anticorps Polyclonal de lapin anti-OSGIN1

• Phare
• Validé par KD/KO

OSGIN1 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, IHC, IP, ELISA

Conjugaison

Non conjugué

Publications(7)

N° de cat : 15248-1-AP

Synonymes

BDGI, BMSC-derived growth inhibitor, Bone marrow stromal cell-derived growth inhibitor, huOKL38, OKL38

---

Galerie de données de validation

• 

  WB analysis using 15248-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 15248-1-AP (OSGIN1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  WB analysis using 15248-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 15248-1-AP (OSGIN1 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

---

Applications testées

• Résultats positifs en WB: cellules A549, tissu hépatique de souris, tissu ovarien de rat, tissu ovarien de souris

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• KD/KO: See 1 publications below
• WB: See 7 publications below
• IHC: See 1 publications below
• IP: See 1 publications below

Informations sur le produit

15248-1-AP cible OSGIN1 dans les applications de WB, IHC, IP, ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Réactivité citée: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: OSGIN1 Protéine recombinante Ag4295
• Nom complet: oxidative stress induced growth inhibitor 1
• Masse moléculaire calculée: 61 kDa
• Poids moléculaire observé: 52 kDa
• Numéro d’acquisition GenBank: BC032476
• Symbole du gène: OSGIN1
• Identification du gène (NCBI): 29948
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

OSGIN1, also named as BDGI and OKL38, belongs to the OKL38 family. OSGIN1 is a gene linked to oxidative stress and cell death in other tissues, was markedly upregulated in smokers compared to nonsmokers (PMID: 28548877). OSGIN1 has 3 isoforms with the molecular mass of 38, 52 and 61 kDa (PMID: 28181536).

Publications

Species	Application	Title
human	WB	J Hazard Mater; METTL3 regulates PM2.5-induced cell injury by targeting OSGIN1 in human airway epithelial cells.; Authors - Qi Yuan
human	WB,IP,IHC	Cell Mol Life Sci; OSGIN1 is a novel TUBB3 regulator that promotes tumor progression and gefitinib resistance in non-small cell lung cancer; Authors - Xiaomeng Xie
human	WB	Toxicol Lett; LncRNA UCA1 attenuates autophagy-dependent cell death through blocking autophagic flux under arsenic stress.; Authors - Ming Gao ; KD Validated
human	WB	J Pharmacol Exp Ther; Mechanistic Analysis of an Extracellular Signal-Regulated Kinase 2-Interacting Compound that Inhibits Mutant BRAF-Expressing Melanoma Cells by Inducing Oxidative Stress.; Authors - Ramon Martinez
human	WB	Toxicol Lett; OSGIN1 regulates PM2.5-induced fibrosis via mediating autophagy in an in vitro model of COPD; Authors - Xiying Tang
mouse	WB	Int J Mol Sci; Methylmercury Induces Apoptosis in Mouse C17.2 Neural Stem Cells through the Induction of OSGIN1 Expression by NRF2; Authors - Naoya Yamashita

{{ptg:RelatedPrimaryAntibodies}}