Anticorps Recombinant de lapin anti-OSMR

OSMR Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241865A6

N° de cat : 84555-1-PBS

Synonymes

Interleukin-31 receptor subunit beta, IL-31R-beta, IL-31RB, IL-31R subunit beta, IL-31 receptor subunit beta

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Galerie de données de validation

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  WB analysis using 84555-1-RR (same clone as 84555-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84555-1-RR (OSMR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84555-1-PBS in a different storage buffer formulation.

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  WB analysis of A375 using 84555-1-RR (same clone as 84555-1-PBS)

  A375 cells were subjected to SDS PAGE followed by western blot with 84555-1-RR (OSMR antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84555-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84555-1-PBS cible OSMR dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: OSMR Protéine recombinante Ag1426
• Nom complet: oncostatin M receptor
• Masse moléculaire calculée: 110 kDa
• Poids moléculaire observé: 150-180 kDa
• Numéro d’acquisition GenBank: BC010943
• Symbole du gène: OSMR
• Identification du gène (NCBI): 9180
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Oncostatin M (OSM) is a member of interleukin-6 family cytokines that modulates proliferation and differentiation in numerous cells (PMID: 22982441). OSM signals via a receptor complex comprising gp130 and the OSMR (also referred to as OSMRβ) (PMID: 8999038). OSMR is a single-pass membrane protein that belongs to the type I cytokine receptor family. OSMR mRNA is expressed relatively high in all neural cells and fibroblast, epithelial, and various tumor cell lines (PMID: 8999038). It has also been shown that OSMR associates with IL31RA to form the heterodimeric IL31 receptor (PMID: 15184896). The predicted molecular weight of OSMR is 110 kDa, and bands of 150-180 kDa can also be detected (PMID:8999038 ;34644107; 30226002; 9188471;22056139).

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