Anticorps Polyclonal de lapin anti-OXGR1

OXGR1 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 22069-1-PBS

Synonymes

2 oxoglutarate receptor 1, Alpha ketoglutarate receptor 1, G protein coupled receptor 80, G protein coupled receptor 99, GPR80

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Galerie de données de validation

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  WB analysis using 22069-1-AP (same clone as 22069-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 22069-1-AP (OXGR1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22069-1-PBS in a different storage buffer formulation.

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Informations sur le produit

22069-1-PBS cible OXGR1 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: OXGR1 Protéine recombinante Ag17186
• Nom complet: oxoglutarate (alpha-ketoglutarate) receptor 1
• Masse moléculaire calculée: 337 aa, 38 kDa
• Poids moléculaire observé: 38-42 kDa
• Numéro d’acquisition GenBank: BC103881
• Symbole du gène: OXGR1
• Identification du gène (NCBI): 27199
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

2-oxoglutarate receptor 1(OXGR1) also known as GPR99, belongs to the G-protein coupled receptor family. OXGR1is expressed in renal cortical connecting tubule and collecting duct type B intercalated cells. When stimulated by its ligand, OXGR1 mediates cellular calcium uptake, which acts as a signal to promote the chloride-bicarbonate exchanger SLC26A4. Dominant loss-of-function OXGR1 variants are associated with recurrent calcium oxalate NL/NC disease(PMID: 36571463).

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