Anticorps Recombinant de lapin anti-P-Selectin/CD62P

P-Selectin/CD62P Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 488 Fluorescent Dye

CloneNo.

240766F5

N° de cat : CL488-98302-2

Synonymes

CD62P, P-selectin, 240766F5, Grmp, P selectin

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Galerie de données de validation

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  FC experiment of mouse peripheral blood platelets using CL488-98302-2

  1x10^6 thrombin-treated mouse peripheral blood platelets were surface stained with 0.25 ug CoraLite®488 Anti-Mouse P-Selectin/CD62P Rabbit RecAb (CL488-98302-2, Clone: 240766F5) (red) or 0.25 ug CoraLite® Plus 488 Rabbit IgG Isotype Control RecAb (CL488-98136, Clone: 240953C9) (blue). 1x10^6 untreated mouse peripheral blood platelets were surface stained with 0.25 ug CoraLite®488 Anti-Mouse P-Selectin/CD62P Rabbit RecAb (CL488-98302-2, Clone: 240766F5)(black, dashed). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Thrombin treated mouse peripheral blood platelets,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL488-98302-2 cible P-Selectin/CD62P dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: P-Selectin/CD62P Protéine recombinante Eg0691
• Nom complet: selectin, platelet
• Masse moléculaire calculée: 83 kDa
• Numéro d’acquisition GenBank: NM_011347.2
• Symbole du gène: Selp
• Identification du gène (NCBI): 20344
• Conjugaison: CoraLite® Plus 488 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 491 nm / 516 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

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