Anticorps Monoclonal anti-P-cadherin

P-cadherin Monoclonal Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

1G10F7

N° de cat : 66295-1-PBS

Synonymes

Cadherin 3, CDH3, CDHP, HJMD, P cadherin, PCAD, P-cadherin, Placental cadherin

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Galerie de données de validation

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  WB analysis of A431 using 66295-1-Ig (same clone as 66295-1-PBS)

  A431 cells were subjected to SDS PAGE followed by western blot with 66295-1-Ig (P-cadherin antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66295-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 66295-1-Ig (same clone as 66295-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 66295-1-Ig (P-cadherin antibody) at dilution of 1:250 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66295-1-PBS in a different storage buffer formulation.

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  IHC staining of human placenta using 66295-1-Ig (same clone as 66295-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 66295-1-Ig (P-cadherin antibody) at dilution of 1:250 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66295-1-PBS in a different storage buffer formulation.

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Informations sur le produit

66295-1-PBS cible P-cadherin dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: P-cadherin Protéine recombinante Ag4758
• Nom complet: cadherin 3, type 1, P-cadherin (placental)
• Masse moléculaire calculée: 829 aa, 91 kDa
• Poids moléculaire observé: 120 kDa
• Numéro d’acquisition GenBank: BC041846
• Symbole du gène: P-cadherin
• Identification du gène (NCBI): 1001
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily which also include E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer.

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