Anticorps Recombinant de lapin anti-P-cadherin

P-cadherin Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

251775F5

N° de cat : 86776-1-PBS

Synonymes

Cadherin 3, Cadherin-3, CDH3, CDHP, HJMD

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Galerie de données de validation

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  WB analysis using 86776-1-RR (same clone as 86776-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86776-1-RR (CDH3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86776-1-PBS in a different storage buffer formulation.

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  WB analysis using 86776-1-RR (same clone as 86776-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86776-1-RR (CDH3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86776-1-PBS in a different storage buffer formulation.

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  IF Staining of A431 using 86776-1-RR (same clone as 86776-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using P-cadherin antibody (86776-1-RR, Clone: 251775F5 ) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 86776-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86776-1-PBS cible P-cadherin dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: P-cadherin Protéine recombinante Eg5236
• Nom complet: cadherin 3, type 1, P-cadherin (placental)
• Masse moléculaire calculée: 91 kDa
• Poids moléculaire observé: 120 kDa
• Numéro d’acquisition GenBank: NM_001793.5
• Symbole du gène: P-cadherin
• Identification du gène (NCBI): 1001
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Cadherins are a family of transmembrane glycoproteins that mediate calcium-dependent cell-cell adhesion and play an important role in the maintenance of normal tissue architecture. P-cadherin (placental cadherin), also known as CDH3 (cadherin 3), is a classical member of the cadherin superfamily which also include E-, N-, R-, and B-cadherins. Aberrant expression of P-cadherin has been reported in many cancers, including breast, gastric, endometrial, ovarian, and prostate cancer.

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