Anticorps Recombinant de lapin anti-P glycoprotein

P glycoprotein Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241512A1

N° de cat : 84295-3-PBS

Synonymes

ABCB1, 241512A1, EC:7.6.2.2, EC:7.6.2.1, ATP-dependent translocase ABCB1

---

Galerie de données de validation

• 

  WB analysis using 84295-3-RR (same clone as 84295-3-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84295-3-RR (P glycoprotein antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84295-3-PBS in a different storage buffer formulation.

---

Informations sur le produit

84295-3-PBS cible P glycoprotein dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: ATP-binding cassette, sub-family B (MDR/TAP), member 1
• Masse moléculaire calculée: 1280 aa, 142 kDa
• Poids moléculaire observé: 130-150 kDa
• Numéro d’acquisition GenBank: BC130424
• Symbole du gène: P glycoprotein
• Identification du gène (NCBI): 5243
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

ABCB1 (also known as P-gp/ P-glycoprotein, MDR1/multidrug-resistance 1) is a plasma membrane protein first discovered in multidrug resistant tumor cells. ABCB1 can extrude a large number of medically relevant compounds from cells and causes drug resistance. ABCB1 is expressed in a variety of human cancers as well as normal tissues including brain, and placenta. Overexpression of ABCB1 correlates with a negative prognosis in several types of cancer.

{{ptg:RelatedPrimaryAntibodies}}