• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Anticorps Recombinant de lapin anti-P2RX6

P2RX6 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241620B10

N° de cat : 84458-4-PBS

Synonymes

P2XM, P2X6, P2X purinoceptor 6, P2RXL1, ATP receptor

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of mouse skeletal muscle tissue using P2RX6 Recombinant antibody (84458-4-RR)

    WB analysis of mouse skeletal muscle using 84458-4-RR (same clone as 84458-4-PBS)

    mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 84458-4-RR (P2RX6 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84458-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84458-4-RR

    Affinity and Kinetic Characterization of 84458-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84458-4-RR against Human P2RX6 were performed. The affinity constant is below 1 pM.

Informations sur le produit

84458-4-PBS cible P2RX6 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

Réactivité Humain, souris
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène P2RX6 Protéine recombinante Ag12331
Nom complet purinergic receptor P2X, ligand-gated ion channel, 6
Masse moléculaire calculée 431 aa, 48 kDa
Poids moléculaire observé 45 kDa
Numéro d’acquisition GenBankBC033488
Symbole du gène P2RX6
Identification du gène (NCBI) 9127
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Protein A purfication
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The P2 receptors have two subfamilies in mammalian cells, P2X and P2Y. P2X family of ligand-gated ion channel receptors have seven members, P2RX1-7, which all constitute non-selective cation channels proposed to be functional under a homo- or heterotrimeric association. P2RX6 is predominantly expressed in skeletal muscle, and regulated by p53. It's reported that ATP might increase renal cell carcinoma cells migration and invasion through P2RX6.(PMID: 31159832, PMID:9242461)

{{ptg:RelatedPrimaryAntibodies}}