Anticorps Polyclonal de lapin anti-PAK7

PAK7 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32085-1-PBS

Synonymes

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Galerie de données de validation

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  WB analysis using 32085-1-AP (same clone as 32085-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32085-1-AP (PAK7 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32085-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32085-1-PBS cible PAK7 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat

• Réactivité: Humain, rat
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PAK7 Protéine recombinante Ag29190
• Nom complet: p21 protein (Cdc42/Rac)-activated kinase 7
• Masse moléculaire calculée: 719 aa, 81 kDa
• Poids moléculaire observé: 80 kDa
• Numéro d’acquisition GenBank: BC024179
• Symbole du gène: PAK7
• Identification du gène (NCBI): 57144
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PAK7, also known as PAK5, is a newly found but scarcely researched type II PAKs (PAK4, 5, 6). PAK7 was originally found in the brain, which promotes filopodia formation in nerve cells. Recently, studies have found that the expression level of PAK7 significantly increased in colorectal cancer, ovarian cancer, gastric cancer, neuroglioma, hepatocellular carcinoma, pancreatic cancer, osteosarcoma, and breast cancer. PAK7 plays an important role in tumorigenesis, invasion, and metastasis, mainly related to its mechanism of regulating cytoskeleton, inhibiting apoptosis, and promoting proliferation. The calculated molecular weight of PAK7 is 80 kDa (PMID: 29805709, PMID: 34165002).

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