Anticorps Polyclonal de lapin anti-PANK4

PANK4 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32953-1-PBS

Synonymes

4'-phosphopantetheine phosphatase, EC:3.1.3.-, hPanK4, Inactive pantothenic acid kinase 4

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Galerie de données de validation

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  WB analysis using 32953-1-AP (same clone as 32953-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 32953-1-AP (PANK4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 32953-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32953-1-PBS cible PANK4 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PANK4 Protéine recombinante Ag38232
• Nom complet: pantothenate kinase 4
• Masse moléculaire calculée: 86 kDa，773aa
• Poids moléculaire observé: 86 kDa
• Numéro d’acquisition GenBank: NM_018216.2
• Symbole du gène: PANK4
• Identification du gène (NCBI): 55229
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PANK4 (Pantothenate Kinase 4) is a member of the pantothenate kinase family, which is involved in the biosynthesis of coenzyme A (CoA). However, unlike other members of the family, PANK4 lacks the residues required for kinase activity and instead contains a phosphatase domain (DUF89) that can dephosphorylate 4'-phosphopantetheine, an intermediate in CoA biosynthesis (PMID: 30927326). This suggests that PANK4 may act as a pseudoenzyme, regulating cellular CoA levels by antagonizing CoA production (PMID: 39746949).

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