Anticorps Polyclonal de lapin anti-PAR2

• Phare
• Validé par KD/KO

PAR2 Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 12160-1-PBS

Synonymes

PAR 2, G-protein coupled receptor 11, GPR11, G protein coupled receptor 11, F2RL1

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Galerie de données de validation

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  WB analysis using 12160-1-AP (same clone as 12160-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12160-1-AP (PAR2 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12160-1-PBS in a different storage buffer formulation.

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Informations sur le produit

12160-1-PBS cible PAR2 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: PAR2 Protéine recombinante Ag2801
• Nom complet: coagulation factor II (thrombin) receptor-like 1
• Masse moléculaire calculée: 397 aa, 44 kDa
• Poids moléculaire observé: 50-55 kDa
• Numéro d’acquisition GenBank: BC018130
• Symbole du gène: PAR2
• Identification du gène (NCBI): 2150
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Proteinase-activated receptors (PARs) are G protein-coupled receptors activated through cleavage of their N-termini by mainly serine proteases. The family of PARs includes four members: PAR1, PAR2, PAR3, and PAR4. PAR2, also known as F2RL1, is expressed in epithelial cells (e.g., lung, gastrointestinal tract), endothelial cells, smooth muscle cells, fibroblasts, nerves, and some immune and inflammatory cells. PAR2 knockout mice and PAR2 agonists and antagonists have implicated PAR2 as a promising target in inflammatory conditions; respiratory, gastrointestinal, metabolic, cardiovascular, and neurological dysfunction; and cancers. (PMID:23895492)

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