Anticorps Recombinant de lapin anti-PAR3

PAR3 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, rat, souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241780F7

N° de cat : 84593-1-PBS

Synonymes

F2RL2, Proteinase-activated receptor 3, PAR-3, PAR 3, Coagulation factor II receptor-like 2

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Galerie de données de validation

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  WB analysis using 84593-1-RR (same clone as 84593-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84593-1-RR (PAR3 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84593-1-PBS in a different storage buffer formulation.

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Informations sur le produit

84593-1-PBS cible PAR3 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain, rat, souris

• Réactivité: Humain, rat, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: coagulation factor II (thrombin) receptor-like 2
• Masse moléculaire calculée: 374 aa, 43 kDa
• Poids moléculaire observé: 45 kDa
• Numéro d’acquisition GenBank: BC093648
• Symbole du gène: PAR3
• Identification du gène (NCBI): 2151
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PAR3 is a crucial protein involved in the establishment and maintenance of cell polarity across various species. It plays a significant role in organizing cellular structures and functions, particularly in epithelial and neuronal cells. PAR3 has been implicated in various aspects of cancer biology. It can act as a tumor suppressor in epithelial cancers, and its expression or mutations have been associated with the progression and behavior of glioblastoma, pancreatic cancer, and other malignancies.

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