Anticorps Recombinant de lapin anti-PARP14

PARP14 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain, souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241078C11

N° de cat : 84039-6-PBS

Synonymes

PARP 14, KIAA1268, BAL2, 241078C11

---

Galerie de données de validation

• 

  WB analysis using 84039-6-RR (same clone as 84039-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84039-6-RR (PARP14 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84039-6-PBS in a different storage buffer formulation.

• 

  IHC staining of mouse colon using 84039-6-RR (same clone as 84039-6-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse colon tissue slide using 84039-6-RR (PARP14 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84039-6-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84039-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84039-6-RR against Human PARP14 were performed. The affinity constant is 0.685 nM.

---

Informations sur le produit

84039-6-PBS cible PARP14 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain, souris

• Réactivité: Humain, souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: PARP14 Protéine recombinante Ag35007
• Nom complet: poly (ADP-ribose) polymerase family, member 14
• Masse moléculaire calculée: 203kd
• Poids moléculaire observé: 200 kDa
• Numéro d’acquisition GenBank: NM_017554
• Symbole du gène: PARP14
• Identification du gène (NCBI): 54625
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

PARP14 (poly (ADP-ribose) polymerase family, member 14) is a PARP family member that has roles in DNA repair, B cell regulation, and focal adhesion (PMID: 25753673). The largest of all the human PARPs is PARP14. PARP14 has been reported to regulate several different pathways involved in immunity, inflammation, and genome stability (PMID: 37703374).

{{ptg:RelatedPrimaryAntibodies}}